Services will be diverted “where possible” and buses will replace trains on part of the journey on each route during the work.
The service changes will run from Sunday until October 22, then from from October 28 until November 25.
Along the 50km route engineers will be working both day and night to complete overhead line electrification (OLE) work including mast and cantilever installation, cable ducting work on platforms at stations along the route and aligning newly-installed infrastructure.
Paul Reilly, Network Rail programme manager, said: “Electrification will transform travel across the Central Belt of Scotland and is part of our commitment to delivering the best railway Scotland has ever had.
“Our engineers will be working around the clock to complete the electrification in time for the introduction of the new fleet of electric trains in December.
“We understand the inconvenience these works will cause to some passengers and residents and we are working hard to keep disruption to a minimum.
“We are encouraging customers to leave extra time for travel, and plan journeys in advance. All train and bus times are available at www.scotrail.co.uk as well as on the ScotRail app.”
Routes affected by changes are: -
Sundays, September 2 until October 21 -
Edinburgh – Dunblane / Perth
Glasgow Queen St – Alloa
Glasgow Queen Street – Aberdeen
Glasgow Queen St – Inverness / Elgin
Sundays October 28 until November 25 2018 (from 9pm Sunday evening)
Edinburgh – Dunblane / Perth services
Glasgow Queen St – Alloa services
Glasgow Queen St / Edinburgh – Inverness / Elgin services
Glasgow Queen St – Aberdeen services