Pete Firman was due to play Falkirk Town Hall on Saturday.
Organisers said the show had been pulled due to “unforeseen filming commitments which are unavoidable”.
A spokeswoman for the Scottish Comedy Agency said: “We wish to apologise to all those who were looking forward to the event, and assure everyone who has purchased tickets that they can transfer to another Funny in Falkirk show or be issued with a full refund.
“Customers are advised to contact the original point of sale ticket vendor.”
The third annual Funny in Falkirk kicks-off on Friday with performances from Bruce Morton and Gary Little.
The festival runs from July 20 - 31.
Tickets for Funny in Falkirk, including shows by the likes of Mark Watson, Des Clarke and Tome Stade, can be bought from The Steeple box office in Falkirk High Street or by visiting www.funnyinfalkirk.com.