The quartet revealed the news along with a number of European tour dates this morning, and anticipation of a full UK tour, along with new material is already mounting.
The festival is being held over two weekends (June 29 to July 1 and July 6 to July 8), and Alex Turner and company are penned in to play the opening weekend's Sunday as headliners.
Joining the R U Mine? performers on the Sunday are acts Interpol, Blossoms, Nothing But Thieves, Declan McKenna, Miles Kane and Tom Grennan.
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This will be the group's first gig on UK soil since they played Leeds festival on August 24, 2014.
Tickets for Sunday 1st July at TRSNMT will go on pre-sale at 9am on Tuesday 30th January from TRNSMTfest.com.
Full Arctic Monkeys tour dates
June 2, 2018
Primavera Sound Festival - Barcelona, Spain
June 8, 2018
Best Kept Secret - Hilvarenbeek, Netherlands
June, 14-17, 2018
Firefly Festival - Dover, United States
June 22-24, 2018
Southside Festival - Neuhausen Ob Eck, Germany
June 22-24 2018
Hurricane Festival - Scheesel, Germany
July 1, 2018
TRNSMT - Glasgow, Scotland
July 4, 2018
Open'er Festival - Gdynia, Poland
July 6, 2018
Rockwave Festival - Athens, Greece
July 8, 2018
Rock Werchter - Werchter, Belgium
July 12, 2018
Nos Alive Festival - Lisbon, Portugal
July 13, 2018
Mad Cool Festival - Madrid, Spain
August 8, 2018
Oya Festival - Oslo, Norway
August 9-11, 2018
Way Out Festival - Gothenburg, Sweden
August 11, 2018
Flow Festival - Helsinki, Finland
August 14, 2018
Sziget Festival - Budapest, Hungary